AMBIEN CR vs BUTABARBITAL SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. AMBIEN CR and BUTABARBITAL SODIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMBIEN CR	BUTABARBITAL SODIUM
Rating	70/100	56/100
Pharmacy pays	~$1.04 /30	—
Type	RX	RX
Active ingredient	ZOLPIDEM TARTRATE	BUTABARBITAL SODIUM
Manufacturer	Cosette	Teva
Dosage forms	Tablet	Tablet
Drug class	Gamma-Aminobutyric Acid A Receptor Positive Modulator	—
Boxed warning	Boxed warning	None
Half-life	about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults	—
Treats	Sleep Initiation and Maintenance Disorders	Sleep Initiation and Maintenance Disorders

ambien cr butabarbital sodium

Rating

70/100

56/100

Pharmacy pays

~$1.04 /30

—

Type

Active ingredient

ZOLPIDEM TARTRATE

BUTABARBITAL SODIUM

Manufacturer

Cosette

Teva

Dosage forms

Tablet

Drug class

Gamma-Aminobutyric Acid A Receptor Positive Modulator

—

Boxed warning

None

Half-life

about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults

—

Treats

Sleep Initiation and Maintenance Disorders

Frequently asked questions

Which is better-rated, Ambien CR or Butabarbital Sodium?

By our independent rating, Ambien CR scores higher — 3.5 vs 2.8 out of 5 for Butabarbital Sodium. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Ambien CR and Butabarbital Sodium?

Ambien CR contains Zolpidem Tartrate, while Butabarbital Sodium contains Butabarbital Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.