ALYFTREK vs COLAZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. ALYFTREK and COLAZAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALYFTREK	COLAZAL
Rating	New	74/100
Pharmacy pays	—	~$11.02 /30
Type	RX	RX
Active ingredient	DEUTIVACAFTOR AND TEZACAFTOR AND VANZACAFTOR CALCIUM	BALSALAZIDE DISODIUM
Manufacturer	Vertex Pharms Inc	Valeant Pharm Intl
Dosage forms	Tablet	Capsule
Drug class	—	Aminosalicylate
Boxed warning	Boxed warning	None
Treats	—	Ulcerative Colitis

alyftrek colazal

Rating

New

74/100

Pharmacy pays

—

~$11.02 /30

Type

Active ingredient

DEUTIVACAFTOR AND TEZACAFTOR AND VANZACAFTOR CALCIUM

BALSALAZIDE DISODIUM

Manufacturer

Vertex Pharms Inc

Valeant Pharm Intl

Dosage forms

Tablet

Capsule

Drug class

—

Aminosalicylate

Boxed warning

None

Treats

—

Ulcerative Colitis

Frequently asked questions

What is the difference between Alyftrek and Colazal?

Alyftrek contains Deutivacaftor and Tezacaftor and Vanzacaftor Calcium, while Colazal contains Balsalazide Disodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.