ALSUMA vs ONZETRA XSAIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ALSUMA	ONZETRA XSAIL
Rating	New	New
Pharmacy pays	~$481.89 /30	~$481.89 /30
Type	RX	RX
Active ingredient	SUMATRIPTAN SUCCINATE	SUMATRIPTAN SUCCINATE
Manufacturer	Meridian Medcl	Currax
Dosage forms	Injectable	Capsule
Drug class	Serotonin-1b and Serotonin-1d Receptor Agonist	Serotonin-1b and Serotonin-1d Receptor Agonist
Boxed warning	None	None
Half-life	about 2 hours (terminal elimination half-life 115 ± 19 minutes)	about 2 hours (terminal elimination half-life 115 ± 19 minutes)
Treats	Cluster Headache, Migraine Disorders	Cluster Headache, Migraine Disorders

alsuma onzetra xsail

Rating

New

Pharmacy pays

~$481.89 /30

Type

Active ingredient

SUMATRIPTAN SUCCINATE

Manufacturer

Meridian Medcl

Currax

Dosage forms

Injectable

Capsule

Drug class

Serotonin-1b and Serotonin-1d Receptor Agonist

Boxed warning

None

Half-life

about 2 hours (terminal elimination half-life 115 ± 19 minutes)

Treats

Cluster Headache, Migraine Disorders

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Frequently asked questions

Which is cheaper, Alsuma or Onzetra Xsail?

Pharmacies pay about the same to acquire either one — roughly $481.89 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Alsuma and Onzetra Xsail?

Both Alsuma and Onzetra Xsail share the active ingredient Sumatriptan Succinate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.