ALOXI vs ONDANSETRON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ALOXI and ONDANSETRON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALOXI	ONDANSETRON
Rating	New	56/100
Pharmacy pays	—	$0.15 /mL
Type	RX	RX
Active ingredient	PALONOSETRON HYDROCHLORIDE	ONDANSETRON
Manufacturer	Helsinn Hlthcare	Teva
Dosage forms	Injectable	Injectable, Solution, Tablet, Tablet, orally disintegrating
Drug class	Serotonin-3 Receptor Antagonist	Serotonin-3 Receptor Antagonist
Boxed warning	None	None
Half-life	—	about 3 to 5 hours (roughly 4 hours) in healthy adults
Treats	—	Alcoholism

aloxi ondansetron

Rating

New

56/100

Pharmacy pays

—

$0.15 /mL

Type

Active ingredient

PALONOSETRON HYDROCHLORIDE

ONDANSETRON

Manufacturer

Helsinn Hlthcare

Teva

Dosage forms

Injectable

Injectable, Solution, Tablet, Tablet, orally disintegrating

Drug class

Serotonin-3 Receptor Antagonist

Boxed warning

None

Half-life

—

about 3 to 5 hours (roughly 4 hours) in healthy adults

Treats

—

Alcoholism

Frequently asked questions

What is the difference between Aloxi and Ondansetron?

Aloxi contains Palonosetron Hydrochloride, while Ondansetron contains Ondansetron — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.