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ALLOPURINOL vs ZYLOPRIM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$1.66 /30
~$1.66 /30

Type

RX
RX

Active ingredient

ALLOPURINOL
ALLOPURINOL

Dosage forms

Tablet
Tablet

Drug class

Xanthine Oxidase Inhibitor
Xanthine Oxidase Inhibitor

Boxed warning

None
None

Half-life

about 1 to 2 hours (parent drug)
about 1 to 2 hours (parent drug)

Treats

Gout
Gout

Frequently asked questions

Which is cheaper, Allopurinol or Zyloprim?

Pharmacies pay about the same to acquire either one — roughly $1.66 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Allopurinol and Zyloprim?

Both Allopurinol and Zyloprim share the active ingredient Allopurinol.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.