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ALLI vs XENICAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

72/100
New

Pharmacy pays

~$207.04 /30
~$207.04 /30

Type

OTC
RX

Active ingredient

ORLISTAT
ORLISTAT

Dosage forms

Capsule
Capsule

Drug class

Boxed warning

None
None

Treats

Obesity
Obesity

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Where to buy

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Frequently asked questions

Which is cheaper, Alli or Xenical?

Pharmacies pay about the same to acquire either one — roughly $207.04 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Alli and Xenical?

Both Alli and Xenical share the active ingredient Orlistat, but Alli is sold as OTC and Xenical as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.