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ALLI vs DIETHYLPROPION HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Rating

72/100
70/100

Pharmacy pays

~$207.04 /30
~$7.96 /30

Type

OTC
RX

Active ingredient

ORLISTAT
DIETHYLPROPION HYDROCHLORIDE

Dosage forms

Capsule
Tablet

Drug class

Sympathomimetic Amine Anorectic

Boxed warning

None
None

Treats

Obesity
Obesity

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Where to buy

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Frequently asked questions

Which is better-rated, Alli or Diethylpropion Hydrochloride?

By our independent rating, Alli scores higher — 3.6 vs 3.5 out of 5 for Diethylpropion Hydrochloride. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Alli or Diethylpropion Hydrochloride?

Diethylpropion Hydrochloride costs pharmacies less to acquire — about $7.96 vs $207.04 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Alli and Diethylpropion Hydrochloride?

Alli contains Orlistat, while Diethylpropion Hydrochloride contains Diethylpropion Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.