ALLEGRA-D 12 HOUR ALLERGY AND CONGESTION vs FEXOFENADINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ALLEGRA-D 12 HOUR ALLERGY AND CONGESTION	FEXOFENADINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE
Rating	New	New
Pharmacy pays	~$7.44 /30	~$7.44 /30
Type	OTC	RX
Active ingredient	FEXOFENADINE HYDROCHLORIDE AND PSEUDOEPHEDRINE HYDROCHLORIDE	FEXOFENADINE HYDROCHLORIDE AND PSEUDOEPHEDRINE HYDROCHLORIDE
Manufacturer	Chattem Sanofi	Pld Acquisitions LLC
Dosage forms	Tablet, extended release	Tablet, extended release
Drug class	—	—
Boxed warning	None	None
Half-life	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

allegra-d 12 hour allergy and congestion fexofenadine hydrochloride; pseudoephedrine hydrochloride

Rating

New

Pharmacy pays

~$7.44 /30

Type

OTC

Active ingredient

FEXOFENADINE HYDROCHLORIDE AND PSEUDOEPHEDRINE HYDROCHLORIDE

Manufacturer

Chattem Sanofi

Pld Acquisitions LLC

Dosage forms

Tablet, extended release

Drug class

—

Boxed warning

None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

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Frequently asked questions

Which is cheaper, Allegra-D 12 Hour Allergy and Congestion or Fexofenadine Hydrochloride; Pseudoephedrine Hydrochloride?

Pharmacies pay about the same to acquire either one — roughly $7.44 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Allegra-D 12 Hour Allergy and Congestion and Fexofenadine Hydrochloride; Pseudoephedrine Hydrochloride?

Both Allegra-D 12 Hour Allergy and Congestion and Fexofenadine Hydrochloride; Pseudoephedrine Hydrochloride share the active ingredient Fexofenadine Hydrochloride and Pseudoephedrine Hydrochloride, but Allegra-D 12 Hour Allergy and Congestion is sold as OTC and Fexofenadine Hydrochloride; Pseudoephedrine Hydrochloride as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.