ALLEGRA ALLERGY vs XYZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ALLEGRA ALLERGY	XYZAL
Rating	New	New
Pharmacy pays	~$7.33 /30	$0.06 /mL
Type	OTC	RX
Active ingredient	FEXOFENADINE HYDROCHLORIDE	LEVOCETIRIZINE DIHYDROCHLORIDE
Manufacturer	Chattem Sanofi	Chattem Sanofi
Dosage forms	Tablet	Solution, Tablet
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Half-life	about 14 hours (label: mean elimination half-life 14.4 hours)	—
Treats	Perennial Allergic Rhinitis, Urticaria	Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

allegra allergy xyzal

Rating

New

Pharmacy pays

~$7.33 /30

$0.06 /mL

Type

OTC

Active ingredient

FEXOFENADINE HYDROCHLORIDE

LEVOCETIRIZINE DIHYDROCHLORIDE

Manufacturer

Chattem Sanofi

Dosage forms

Tablet

Solution, Tablet

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Half-life

about 14 hours (label: mean elimination half-life 14.4 hours)

—

Treats

Perennial Allergic Rhinitis, Urticaria

Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Allegra Allergy and Xyzal?

Allegra Allergy contains Fexofenadine Hydrochloride, while Xyzal contains Levocetirizine Dihydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.