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ALLEGRA ALLERGY vs PATADAY ONCE DAILY RELIEF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$7.33 /30
$1.23 /g

Type

OTC
OTC

Active ingredient

FEXOFENADINE HYDROCHLORIDE
OLOPATADINE HYDROCHLORIDE

Dosage forms

Tablet
Solution

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Half-life

about 14 hours (label: mean elimination half-life 14.4 hours)

Treats

Perennial Allergic Rhinitis, Urticaria
Allergic Conjunctivitis

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Allegra Allergy and Pataday Once Daily Relief?

Allegra Allergy contains Fexofenadine Hydrochloride, while Pataday Once Daily Relief contains Olopatadine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.