ALIMTA vs FOLOTYN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ALIMTA and FOLOTYN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALIMTA	FOLOTYN
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PEMETREXED DISODIUM	PRALATREXATE
Manufacturer	Lilly	Acrotech Biopharma
Dosage forms	Injectable	Injectable
Drug class	Folate Analog Metabolic Inhibitor	Folate Analog Metabolic Inhibitor
Boxed warning	None	None
Treats	Non-Small-Cell Lung Carcinoma, Mesothelial Neoplasms	Peripheral T-Cell Lymphoma

alimta folotyn

Rating

New

Pharmacy pays

—

Type

Active ingredient

PEMETREXED DISODIUM

PRALATREXATE

Manufacturer

Lilly

Acrotech Biopharma

Dosage forms

Injectable

Drug class

Folate Analog Metabolic Inhibitor

Boxed warning

None

Treats

Non-Small-Cell Lung Carcinoma, Mesothelial Neoplasms

Peripheral T-Cell Lymphoma

Frequently asked questions

What is the difference between Alimta and Folotyn?

Alimta contains Pemetrexed Disodium, while Folotyn contains Pralatrexate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.