ALDURAZYME vs CUPRIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. ALDURAZYME and CUPRIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALDURAZYME	CUPRIMINE
Rating	New	74/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	LARONIDASE	PENICILLAMINE
Manufacturer	Biomarin Pharm	Valeant Pharm Intl
Dosage forms	Injectable	Capsule
Drug class	Hydrolytic Lysosomal Glycosaminoglycan-Specific Enzyme	Antirheumatic Agent
Boxed warning	None	Boxed warning
Treats	Mucopolysaccharidosis I	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

aldurazyme cuprimine

Rating

New

74/100

Pharmacy pays

—

Type

Active ingredient

LARONIDASE

PENICILLAMINE

Manufacturer

Biomarin Pharm

Valeant Pharm Intl

Dosage forms

Injectable

Capsule

Drug class

Hydrolytic Lysosomal Glycosaminoglycan-Specific Enzyme

Antirheumatic Agent

Boxed warning

None

Boxed warning

Treats

Mucopolysaccharidosis I

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

What is the difference between Aldurazyme and Cuprimine?

Aldurazyme contains Laronidase, while Cuprimine contains Penicillamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.