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ALDOMET vs CLONIDINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. ALDOMET and CLONIDINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

~$225.00 /30
~$1.05 /30

Type

RX
RX

Active ingredient

METHYLDOPA
CLONIDINE HYDROCHLORIDE

Dosage forms

Tablet
Injectable, Tablet, Tablet, extended release

Drug class

Central Alpha-2 Adrenergic Agonist
Central Alpha-2 Adrenergic Agonist

Boxed warning

None
None

Half-life

about 105 minutes (roughly 1.75 hours)
about 12 to 16 hours

Treats

Hypertension
Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

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Frequently asked questions

Which is better-rated, Aldomet or Clonidine Hydrochloride?

By our independent rating, Clonidine Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Aldomet. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Aldomet or Clonidine Hydrochloride?

Clonidine Hydrochloride costs pharmacies less to acquire — about $1.05 vs $225.00 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Aldomet and Clonidine Hydrochloride?

Aldomet contains Methyldopa, while Clonidine Hydrochloride contains Clonidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.