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ALDARA vs ZYCLARA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$350.38 /30
~$350.38 /30

Type

RX
RX

Active ingredient

IMIQUIMOD
IMIQUIMOD

Manufacturer

Dosage forms

Topical
Topical

Drug class

Boxed warning

None
None

Treats

Basal Cell Carcinoma, Condylomata Acuminata, Actinic Keratosis
Basal Cell Carcinoma, Condylomata Acuminata, Actinic Keratosis

Frequently asked questions

Which is cheaper, Aldara or Zyclara?

Pharmacies pay about the same to acquire either one — roughly $350.38 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Aldara and Zyclara?

Both Aldara and Zyclara share the active ingredient Imiquimod.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.