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ALDACTAZIDE vs SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

64/100
70/100

Pharmacy pays

~$0.91 /30
~$0.91 /30

Type

RX
RX

Active ingredient

HYDROCHLOROTHIAZIDE AND SPIRONOLACTONE
HYDROCHLOROTHIAZIDE AND SPIRONOLACTONE

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

Boxed warning

None
None

Half-life

about 6 to 15 hours (the label reports a range, not a single number)
about 6 to 15 hours (the label reports a range, not a single number)

Frequently asked questions

Which is better-rated, Aldactazide or Spironolactone W/ Hydrochlorothiazide?

By our independent rating, Spironolactone W/ Hydrochlorothiazide scores higher — 3.5 vs 3.2 out of 5 for Aldactazide. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Aldactazide or Spironolactone W/ Hydrochlorothiazide?

Pharmacies pay about the same to acquire either one — roughly $0.91 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Aldactazide and Spironolactone W/ Hydrochlorothiazide?

Both Aldactazide and Spironolactone W/ Hydrochlorothiazide share the active ingredient Hydrochlorothiazide and Spironolactone.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.