ALDACTAZIDE vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. ALDACTAZIDE and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALDACTAZIDE	MYSOLINE
Rating	60/100	74/100
Pharmacy pays	~$0.91 /30	~$2.89 /30
Type	RX	RX
Active ingredient	HYDROCHLOROTHIAZIDE AND SPIRONOLACTONE	PRIMIDONE
Manufacturer	Pfizer	Valeant Pharm Intl
Dosage forms	Tablet	Tablet
Drug class	—	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	about 6 to 15 hours (the label reports a range, not a single number)	—
Treats	—	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

aldactazide mysoline

Rating

60/100

74/100

Pharmacy pays

~$0.91 /30

~$2.89 /30

Type

Active ingredient

HYDROCHLOROTHIAZIDE AND SPIRONOLACTONE

PRIMIDONE

Manufacturer

Pfizer

Valeant Pharm Intl

Dosage forms

Tablet

Drug class

—

Anti-Epileptic Agent

Boxed warning

None

Half-life

about 6 to 15 hours (the label reports a range, not a single number)

—

Treats

—

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

Which is better-rated, Aldactazide or Mysoline?

By our independent rating, Mysoline scores higher — 3.7 vs 3.0 out of 5 for Aldactazide. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Aldactazide or Mysoline?

Aldactazide costs pharmacies less to acquire — about $0.91 vs $2.89 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Aldactazide and Mysoline?

Aldactazide contains Hydrochlorothiazide and Spironolactone, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.