ALDACTAZIDE vs COLAZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. ALDACTAZIDE and COLAZAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALDACTAZIDE	COLAZAL
Rating	60/100	74/100
Pharmacy pays	~$0.91 /30	~$11.02 /30
Type	RX	RX
Active ingredient	HYDROCHLOROTHIAZIDE AND SPIRONOLACTONE	BALSALAZIDE DISODIUM
Manufacturer	Pfizer	Valeant Pharm Intl
Dosage forms	Tablet	Capsule
Drug class	—	Aminosalicylate
Boxed warning	None	None
Half-life	about 6 to 15 hours (the label reports a range, not a single number)	—
Treats	—	Ulcerative Colitis

aldactazide colazal

Rating

60/100

74/100

Pharmacy pays

~$0.91 /30

~$11.02 /30

Type

Active ingredient

HYDROCHLOROTHIAZIDE AND SPIRONOLACTONE

BALSALAZIDE DISODIUM

Manufacturer

Pfizer

Valeant Pharm Intl

Dosage forms

Tablet

Capsule

Drug class

—

Aminosalicylate

Boxed warning

None

Half-life

about 6 to 15 hours (the label reports a range, not a single number)

—

Treats

—

Ulcerative Colitis

Frequently asked questions

Which is better-rated, Aldactazide or Colazal?

By our independent rating, Colazal scores higher — 3.7 vs 3.0 out of 5 for Aldactazide. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Aldactazide or Colazal?

Aldactazide costs pharmacies less to acquire — about $0.91 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Aldactazide and Colazal?

Aldactazide contains Hydrochlorothiazide and Spironolactone, while Colazal contains Balsalazide Disodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.