Skip to content
ppharmaranks
Menu
CompaniesProductsDrug classesConditionsBest by conditionTreatmentsInteraction checkerFood & medicinesWhat pharmacies payPill identifierMedicines & breastfeedingChildren’s dosage chartsDo medicines expire?Crushing & splitting pillsHow long meds take to workAlternating Tylenol & ibuprofenDrug recallsSupplementsSafety & lawsuitsGuidesA–ZHow we rate

AFRINOL vs PSEUDOEPHEDRINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
afrinolpseudoephedrine hydrochloride

Rating

New
New

Pharmacy pays

~$8.29 /30
~$8.29 /30

Type

RX
OTC

Active ingredient

PSEUDOEPHEDRINE SULFATE
PSEUDOEPHEDRINE HYDROCHLORIDE

Manufacturer

Schering Plough
Sun Pharm Inds Inc

Dosage forms

Tablet, extended release
Tablet, Tablet, extended release

Drug class

Alpha-Adrenergic Agonist
Alpha-Adrenergic Agonist

Boxed warning

None
None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)
roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

Treats

Asthma, Common Cold, Perennial Allergic Rhinitis
Asthma, Common Cold, Perennial Allergic Rhinitis

Get afrinolhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is cheaper, Afrinol or Pseudoephedrine Hydrochloride?

Pharmacies pay about the same to acquire either one — roughly $8.29 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Afrinol and Pseudoephedrine Hydrochloride?

Afrinol contains Pseudoephedrine Sulfate, while Pseudoephedrine Hydrochloride contains Pseudoephedrine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.