AFINITOR vs COMETRIQ

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. AFINITOR and COMETRIQ are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AFINITOR	COMETRIQ
Rating	70/100	New
Pharmacy pays	~$234.69 /30	—
Type	RX	RX
Active ingredient	EVEROLIMUS	CABOZANTINIB S-MALATE
Manufacturer	Novartis	Exelixis
Dosage forms	Tablet	Capsule, Kit
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Half-life	about 30 hours (mean terminal elimination half-life)	—
Treats	—	Renal Cell Carcinoma

afinitor cometriq

Rating

70/100

New

Pharmacy pays

~$234.69 /30

—

Type

Active ingredient

EVEROLIMUS

CABOZANTINIB S-MALATE

Manufacturer

Novartis

Exelixis

Dosage forms

Tablet

Capsule, Kit

Drug class

Kinase Inhibitor

Boxed warning

None

Half-life

about 30 hours (mean terminal elimination half-life)

—

Treats

—

Renal Cell Carcinoma

Frequently asked questions

What is the difference between Afinitor and Cometriq?

Afinitor contains Everolimus, while Cometriq contains Cabozantinib S-Malate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.