ADZENYS ER vs LISDEXAMFETAMINE DIMESYLATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ADZENYS ER and LISDEXAMFETAMINE DIMESYLATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADZENYS ER	LISDEXAMFETAMINE DIMESYLATE
Rating	New	70/100
Pharmacy pays	~$478.55 /30	—
Type	RX	RX
Active ingredient	AMPHETAMINE	LISDEXAMFETAMINE DIMESYLATE
Manufacturer	Neos Theraps Inc	Ascent Pharms Inc
Dosage forms	Suspension, extended release	Capsule, Tablet, chewable
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	None	Boxed warning
Half-life	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults	less than 1 hour (parent drug)
Treats	Attention Deficit Disorder with Hyperactivity, Narcolepsy	Attention Deficit Disorder with Hyperactivity, Binge Drinking

adzenys er lisdexamfetamine dimesylate

Rating

New

70/100

Pharmacy pays

~$478.55 /30

—

Type

Active ingredient

AMPHETAMINE

LISDEXAMFETAMINE DIMESYLATE

Manufacturer

Neos Theraps Inc

Ascent Pharms Inc

Dosage forms

Suspension, extended release

Capsule, Tablet, chewable

Drug class

Central Nervous System Stimulant

Boxed warning

None

Boxed warning

Half-life

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

less than 1 hour (parent drug)

Treats

Attention Deficit Disorder with Hyperactivity, Narcolepsy

Attention Deficit Disorder with Hyperactivity, Binge Drinking

Frequently asked questions

What is the difference between Adzenys ER and Lisdexamfetamine Dimesylate?

Adzenys ER contains Amphetamine, while Lisdexamfetamine Dimesylate contains Lisdexamfetamine Dimesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.