ADZENYS ER vs CAFCIT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ADZENYS ER and CAFCIT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADZENYS ER	CAFCIT
Rating	New	72/100
Pharmacy pays	~$478.55 /30	~$2.58 /30
Type	RX	RX
Active ingredient	AMPHETAMINE	CAFFEINE CITRATE
Manufacturer	Neos Theraps Inc	Hikma
Dosage forms	Suspension, extended release	Injectable
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	None	None
Half-life	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults	—
Treats	Attention Deficit Disorder with Hyperactivity, Narcolepsy	Apnea, Fatigue

adzenys er cafcit

Rating

New

72/100

Pharmacy pays

~$478.55 /30

~$2.58 /30

Type

Active ingredient

AMPHETAMINE

CAFFEINE CITRATE

Manufacturer

Neos Theraps Inc

Hikma

Dosage forms

Suspension, extended release

Injectable

Drug class

Central Nervous System Stimulant

Boxed warning

None

Half-life

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

—

Treats

Attention Deficit Disorder with Hyperactivity, Narcolepsy

Apnea, Fatigue

Frequently asked questions

Which is cheaper, Adzenys ER or Cafcit?

Cafcit costs pharmacies less to acquire — about $2.58 vs $478.55 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Adzenys ER and Cafcit?

Adzenys ER contains Amphetamine, while Cafcit contains Caffeine Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.