ADVIL vs PEPCID COMPLETE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Attribute	ADVIL	PEPCID COMPLETE
Rating	72/100	70/100
Pharmacy pays	$0.04 /mL	~$0.24 /30
Type	OTC	OTC
Active ingredient	IBUPROFEN	CALCIUM CARBONATE AND FAMOTIDINE AND MAGNESIUM HYDROXIDE
Manufacturer	Haleon US Holdings	Kenvue Brands
Dosage forms	Tablet, Capsule	Tablet, chewable
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 1.8 to 2.0 hours	2.5 to 3.5 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	—

advil pepcid complete

Rating

72/100

70/100

Pharmacy pays

$0.04 /mL

~$0.24 /30

Type

OTC

Active ingredient

IBUPROFEN

CALCIUM CARBONATE AND FAMOTIDINE AND MAGNESIUM HYDROXIDE

Manufacturer

Haleon US Holdings

Kenvue Brands

Dosage forms

Tablet, Capsule

Tablet, chewable

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

2.5 to 3.5 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

—

Get advilhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Where to buy

Buy over-the-counter from trusted retailers.

AmazonCheck price on Amazon

Frequently asked questions

Which is better-rated, Advil or Pepcid Complete?

By our independent rating, Advil scores higher — 3.6 vs 3.5 out of 5 for Pepcid Complete. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Advil and Pepcid Complete?

Advil contains Ibuprofen, while Pepcid Complete contains Calcium Carbonate and Famotidine and Magnesium Hydroxide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.