ADVIL vs VICKS NYQUIL COLD & FLU

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	ADVIL	VICKS NYQUIL COLD & FLU
Rating	72/100	New
Pharmacy pays	$0.04 /mL	—
Type	OTC	OTC
Active ingredient	IBUPROFEN	Acetaminophen, dextromethorphan and doxylamine
Manufacturer	Haleon US Holdings	Procter and Gamble
Dosage forms	Tablet, Capsule	Liquid
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 1.8 to 2.0 hours	—
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	—

advil vicks nyquil cold & flu

Rating

72/100

New

Pharmacy pays

$0.04 /mL

—

Type

OTC

Active ingredient

IBUPROFEN

Acetaminophen, dextromethorphan and doxylamine

Manufacturer

Haleon US Holdings

Procter and Gamble

Dosage forms

Tablet, Capsule

Liquid

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

—

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Frequently asked questions

What is the difference between Advil and Vicks Nyquil Cold & Flu?

Advil contains Ibuprofen, while Vicks Nyquil Cold & Flu contains Acetaminophen, Dextromethorphan and Doxylamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.