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ADVIL vs MOTRIN MIGRAINE PAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Rating

72/100
70/100

Pharmacy pays

$0.04 /mL
$0.04 /mL

Type

OTC
RX

Active ingredient

IBUPROFEN
IBUPROFEN

Dosage forms

Tablet, Capsule
Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

about 1.8 to 2.0 hours
about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Get advilhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is better-rated, Advil or Motrin Migraine Pain?

By our independent rating, Advil scores higher — 3.6 vs 3.5 out of 5 for Motrin Migraine Pain. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Advil or Motrin Migraine Pain?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Advil and Motrin Migraine Pain?

Both Advil and Motrin Migraine Pain share the active ingredient Ibuprofen, but Advil is sold as OTC and Motrin Migraine Pain as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.