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ADVIL vs ADVIL PM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

72/100
72/100

Pharmacy pays

$0.04 /mL
$0.04 /mL

Type

OTC
OTC

Active ingredient

IBUPROFEN
DIPHENHYDRAMINE HYDROCHLORIDE AND IBUPROFEN

Dosage forms

Tablet, Capsule
Capsule, Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

about 1.8 to 2.0 hours
about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is better-rated, Advil or Advil Pm?

Advil and Advil Pm are tied at 3.6 out of 5 by our independent rating.

Which is cheaper, Advil or Advil Pm?

Advil Pm costs pharmacies less to acquire — about $0.04 vs $0.04 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Advil and Advil Pm?

Advil contains Ibuprofen, while Advil Pm contains Diphenhydramine Hydrochloride and Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.