ADVIL CONGESTION RELIEF vs MUCINEX DM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	ADVIL CONGESTION RELIEF	MUCINEX DM
Rating	72/100	New
Pharmacy pays	$0.04 /mL	~$2.55 /30
Type	OTC	OTC
Active ingredient	IBUPROFEN AND PHENYLEPHRINE HYDROCHLORIDE	DEXTROMETHORPHAN HYDROBROMIDE AND GUAIFENESIN
Manufacturer	Haleon US Holdings	Rb Hlth
Dosage forms	Tablet	Tablet, extended release
Drug class	—	—
Boxed warning	None	None
Half-life	about 1.8 to 2.0 hours	—

advil congestion relief mucinex dm

Rating

72/100

New

Pharmacy pays

$0.04 /mL

~$2.55 /30

Type

OTC

Active ingredient

IBUPROFEN AND PHENYLEPHRINE HYDROCHLORIDE

DEXTROMETHORPHAN HYDROBROMIDE AND GUAIFENESIN

Manufacturer

Haleon US Holdings

Rb Hlth

Dosage forms

Tablet

Tablet, extended release

Drug class

—

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

—

Get advil congestion reliefhigher-rated option

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Frequently asked questions

What is the difference between Advil Congestion Relief and Mucinex Dm?

Advil Congestion Relief contains Ibuprofen and Phenylephrine Hydrochloride, while Mucinex Dm contains Dextromethorphan Hydrobromide and Guaifenesin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.