ADVIL COLD AND SINUS vs CHILDREN'S MOTRIN COLD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Attribute	ADVIL COLD AND SINUS	CHILDREN'S MOTRIN COLD
Rating	72/100	70/100
Pharmacy pays	$0.04 /mL	$0.04 /mL
Type	OTC	OTC
Active ingredient	IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE	IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE
Manufacturer	Haleon US Holdings	Kenvue Brands
Dosage forms	Capsule, Tablet	Suspension
Drug class	—	—
Boxed warning	None	None
Half-life	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

advil cold and sinus children's motrin cold

Rating

72/100

70/100

Pharmacy pays

$0.04 /mL

Type

OTC

Active ingredient

IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE

Manufacturer

Haleon US Holdings

Kenvue Brands

Dosage forms

Capsule, Tablet

Suspension

Drug class

—

Boxed warning

None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

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Where to buy

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Frequently asked questions

Which is better-rated, Advil Cold and Sinus or Children's Motrin Cold?

By our independent rating, Advil Cold and Sinus scores higher — 3.6 vs 3.5 out of 5 for Children's Motrin Cold. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Advil Cold and Sinus or Children's Motrin Cold?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Advil Cold and Sinus and Children's Motrin Cold?

Both Advil Cold and Sinus and Children's Motrin Cold share the active ingredient Ibuprofen and Pseudoephedrine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.