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ADVIL COLD AND SINUS vs CHILDREN'S ADVIL COLD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Rating

72/100
72/100

Pharmacy pays

$0.04 /mL
$0.04 /mL

Type

OTC
OTC

Active ingredient

IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE
IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE

Dosage forms

Capsule, Tablet
Suspension

Drug class

Boxed warning

None
None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)
roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is better-rated, Advil Cold and Sinus or Children's Advil Cold?

Advil Cold and Sinus and Children's Advil Cold are tied at 3.6 out of 5 by our independent rating.

Which is cheaper, Advil Cold and Sinus or Children's Advil Cold?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Advil Cold and Sinus and Children's Advil Cold?

Both Advil Cold and Sinus and Children's Advil Cold share the active ingredient Ibuprofen and Pseudoephedrine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.