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ADVIL ALLERGY SINUS vs AVAGARD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Rating

72/100
New

Pharmacy pays

~$0.41 /30

Type

OTC
OTC

Active ingredient

CHLORPHENIRAMINE MALEATE AND IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE
ALCOHOL AND CHLORHEXIDINE GLUCONATE

Dosage forms

Tablet
Topical

Drug class

Boxed warning

None
None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Advil Allergy Sinus and Avagard?

Advil Allergy Sinus contains Chlorpheniramine Maleate and Ibuprofen and Pseudoephedrine Hydrochloride, while Avagard contains Alcohol and Chlorhexidine Gluconate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.