ADEMPAS vs LETAIRIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 11, 2026·How we rate

Possible drug interaction. ADEMPAS and LETAIRIS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADEMPAS	LETAIRIS
Rating	New	70/100
Pharmacy pays	—	~$255.61 /30
Type	RX	RX
Active ingredient	RIOCIGUAT	AMBRISENTAN
Manufacturer	Bayer Hlthcare	Gilead Sciences Inc
Dosage forms	Tablet	Tablet
Drug class	Soluble Guanylate Cyclase Stimulator	Endothelin Receptor Antagonist
Boxed warning	Boxed warning	Boxed warning
Treats	Pulmonary Hypertension	Pulmonary Hypertension

adempas letairis

Rating

New

70/100

Pharmacy pays

—

~$255.61 /30

Type

Active ingredient

RIOCIGUAT

AMBRISENTAN

Manufacturer

Bayer Hlthcare

Gilead Sciences Inc

Dosage forms

Tablet

Drug class

Soluble Guanylate Cyclase Stimulator

Endothelin Receptor Antagonist

Boxed warning

Treats

Pulmonary Hypertension

Frequently asked questions

What is the difference between Adempas and Letairis?

Adempas contains Riociguat, while Letairis contains Ambrisentan — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.