ADDERALL vs RETIN-A

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated September 11, 2026·How we rate

Possible drug interaction. ADDERALL and RETIN-A are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADDERALL	RETIN-A
Rating	32/100	74/100
Pharmacy pays	—	$1.05 /g
Type	RX	RX
Active ingredient	DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE, AND AMPHETAMINE SULFATE	TRETINOIN
Manufacturer	Teva Pharms USA	Valeant Pharm Intl
Dosage forms	Tablet	Topical
Drug class	—	Retinoid
Boxed warning	Boxed warning	None
Half-life	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults	—
Treats	—	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

adderall retin-a

Rating

32/100

74/100

Pharmacy pays

—

$1.05 /g

Type

Active ingredient

DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE, AND AMPHETAMINE SULFATE

TRETINOIN

Manufacturer

Teva Pharms USA

Valeant Pharm Intl

Dosage forms

Tablet

Topical

Drug class

—

Retinoid

Boxed warning

None

Half-life

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

—

Treats

—

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

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Frequently asked questions

Which is better-rated, Adderall or Retin-A?

By our independent rating, Retin-A scores higher — 3.7 vs 1.6 out of 5 for Adderall. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Adderall and Retin-A?

Adderall contains Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate, while Retin-A contains Tretinoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.