ADDERALL XR vs CUPRIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. ADDERALL XR and CUPRIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADDERALL XR	CUPRIMINE
Rating	New	74/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE	PENICILLAMINE
Manufacturer	Takeda Pharms USA	Valeant Pharm Intl
Dosage forms	Capsule, extended release	Capsule
Drug class	—	Antirheumatic Agent
Boxed warning	Boxed warning	Boxed warning
Half-life	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults	—
Treats	—	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

adderall xr cuprimine

Rating

New

74/100

Pharmacy pays

—

Type

Active ingredient

DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE

PENICILLAMINE

Manufacturer

Takeda Pharms USA

Valeant Pharm Intl

Dosage forms

Capsule, extended release

Capsule

Drug class

—

Antirheumatic Agent

Boxed warning

Half-life

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

—

Treats

—

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

What is the difference between Adderall XR and Cuprimine?

Adderall XR contains Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate and Amphetamine Aspartate, while Cuprimine contains Penicillamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.