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ACYCLOVIR vs ULESFIA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ACYCLOVIR and ULESFIA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

56/100
70/100

Pharmacy pays

~$4.83 /30

Type

RX
RX

Active ingredient

ACYCLOVIR
BENZYL ALCOHOL

Manufacturer

Dosage forms

Topical, Capsule, Injectable, Solution, Suspension, Tablet
Topical

Drug class

Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor

Boxed warning

None
None

Half-life

about 2.5 to 3.3 hours

Treats

Chickenpox, Herpes Genitalis, Herpes Labialis
Herpes Labialis, Lice Infestations

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Frequently asked questions

Which is better-rated, Acyclovir or Ulesfia?

By our independent rating, Ulesfia scores higher — 3.5 vs 2.8 out of 5 for Acyclovir. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Acyclovir and Ulesfia?

Acyclovir contains Acyclovir, while Ulesfia contains Benzyl Alcohol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.