ACYCLOVIR vs AVACLYR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	ACYCLOVIR	AVACLYR
Rating	56/100	New
Pharmacy pays	~$4.83 /30	~$4.83 /30
Type	RX	RX
Active ingredient	ACYCLOVIR	ACYCLOVIR
Manufacturer	Teva	Fera Pharms LLC
Dosage forms	Topical, Capsule, Injectable, Solution, Suspension, Tablet	Topical
Drug class	Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor	Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor
Boxed warning	None	None
Half-life	about 2.5 to 3.3 hours	about 2.5 to 3.3 hours
Treats	Chickenpox, Herpes Genitalis, Herpes Labialis	Chickenpox, Herpes Genitalis, Herpes Labialis

acyclovir avaclyr

Rating

56/100

New

Pharmacy pays

~$4.83 /30

Type

Active ingredient

ACYCLOVIR

Manufacturer

Teva

Fera Pharms LLC

Dosage forms

Topical, Capsule, Injectable, Solution, Suspension, Tablet

Topical

Drug class

Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor

Boxed warning

None

Half-life

about 2.5 to 3.3 hours

Treats

Chickenpox, Herpes Genitalis, Herpes Labialis

Get avaclyr

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is cheaper, Acyclovir or Avaclyr?

Pharmacies pay about the same to acquire either one — roughly $4.83 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Acyclovir and Avaclyr?

Both Acyclovir and Avaclyr share the active ingredient Acyclovir.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.