ACULAR vs ZYLET

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. ACULAR and ZYLET are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	ZYLET
Rating	72/100	New
Pharmacy pays	—	$19.64 /mL
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	LOTEPREDNOL ETABONATE AND TOBRAMYCIN
Manufacturer	Abbvie	Bausch and Lomb
Dosage forms	Drops	Drops
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	—
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular zylet

Rating

72/100

New

Pharmacy pays

—

$19.64 /mL

Type

Active ingredient

KETOROLAC TROMETHAMINE

LOTEPREDNOL ETABONATE AND TOBRAMYCIN

Manufacturer

Abbvie

Bausch and Lomb

Dosage forms

Drops

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

—

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

What is the difference between Acular and Zylet?

Acular contains Ketorolac Tromethamine, while Zylet contains Loteprednol Etabonate and Tobramycin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.