ACULAR vs ZIAC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. ACULAR and ZIAC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	ZIAC
Rating	72/100	New
Pharmacy pays	—	~$5.34 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE
Manufacturer	Abbvie	Teva Branded Pharm
Dosage forms	Drops	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 6 to 15 hours (the label reports a range, not a single number)
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular ziac

Rating

72/100

New

Pharmacy pays

—

~$5.34 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE

Manufacturer

Abbvie

Teva Branded Pharm

Dosage forms

Drops

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 6 to 15 hours (the label reports a range, not a single number)

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

What is the difference between Acular and Ziac?

Acular contains Ketorolac Tromethamine, while Ziac contains Bisoprolol Fumarate and Hydrochlorothiazide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.