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ACULAR vs XYREM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. ACULAR and XYREM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
New

Pharmacy pays

Type

RX
RX

Active ingredient

KETOROLAC TROMETHAMINE
SODIUM OXYBATE

Manufacturer

Dosage forms

Drops
Solution

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 5 to 6 hours

Treats

Allergic Conjunctivitis, Inflammation, Pain
Cataplexy

Frequently asked questions

What is the difference between Acular and Xyrem?

Acular contains Ketorolac Tromethamine, while Xyrem contains Sodium Oxybate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.