ACULAR vs POLYSPORIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. ACULAR and POLYSPORIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	POLYSPORIN
Rating	72/100	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	BACITRACIN ZINC AND POLYMYXIN B SULFATE
Manufacturer	Abbvie	Glaxosmithkline
Dosage forms	Drops	Spray/Inhaler, Topical
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	—
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular polysporin

Rating

72/100

70/100

Pharmacy pays

—

Type

Active ingredient

KETOROLAC TROMETHAMINE

BACITRACIN ZINC AND POLYMYXIN B SULFATE

Manufacturer

Abbvie

Glaxosmithkline

Dosage forms

Drops

Spray/Inhaler, Topical

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

—

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular or Polysporin?

By our independent rating, Acular scores higher — 3.6 vs 3.5 out of 5 for Polysporin. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Acular and Polysporin?

Acular contains Ketorolac Tromethamine, while Polysporin contains Bacitracin Zinc and Polymyxin B Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.