ACULAR vs ORTHO-NOVUM 1/50 21

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 11, 2026·How we rate

Possible drug interaction. ACULAR and ORTHO-NOVUM 1/50 21 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	ORTHO-NOVUM 1/50 21
Rating	72/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	MESTRANOL AND NORETHINDRONE
Manufacturer	Abbvie	Ortho Mcneil Pharm
Dosage forms	Drops	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 8 hours
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular ortho-novum 1/50 21

Rating

72/100

New

Pharmacy pays

—

Type

Active ingredient

KETOROLAC TROMETHAMINE

MESTRANOL AND NORETHINDRONE

Manufacturer

Abbvie

Ortho Mcneil Pharm

Dosage forms

Drops

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 8 hours

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

What is the difference between Acular and Ortho-Novum 1/50 21?

Acular contains Ketorolac Tromethamine, while Ortho-Novum 1/50 21 contains Mestranol and Norethindrone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.