ACULAR vs NEO-HYDELTRASOL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. ACULAR and NEO-HYDELTRASOL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	NEO-HYDELTRASOL
Rating	72/100	70/100
Pharmacy pays	—	~$25.36 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	NEOMYCIN SULFATE AND PREDNISOLONE SODIUM PHOSPHATE
Manufacturer	Abbvie	Merck
Dosage forms	Drops	Topical
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	2 to 4 hours
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular neo-hydeltrasol

Rating

72/100

70/100

Pharmacy pays

—

~$25.36 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

NEOMYCIN SULFATE AND PREDNISOLONE SODIUM PHOSPHATE

Manufacturer

Abbvie

Merck

Dosage forms

Drops

Topical

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

2 to 4 hours

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular or Neo-Hydeltrasol?

By our independent rating, Acular scores higher — 3.6 vs 3.5 out of 5 for Neo-Hydeltrasol. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Acular and Neo-Hydeltrasol?

Acular contains Ketorolac Tromethamine, while Neo-Hydeltrasol contains Neomycin Sulfate and Prednisolone Sodium Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.