ACULAR vs FIORINAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR and FIORINAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	FIORINAL
Rating	72/100	72/100
Pharmacy pays	—	~$0.78 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	ASPIRIN AND BUTALBITAL AND CAFFEINE
Manufacturer	Abbvie	Allergan
Dosage forms	Drops	Tablet, Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 20 minutes (the label also states 0.33 hours) for aspirin itself
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular fiorinal

Rating

72/100

Pharmacy pays

—

~$0.78 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

ASPIRIN AND BUTALBITAL AND CAFFEINE

Manufacturer

Abbvie

Allergan

Dosage forms

Drops

Tablet, Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 20 minutes (the label also states 0.33 hours) for aspirin itself

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular or Fiorinal?

Acular and Fiorinal are tied at 3.6 out of 5 by our independent rating.

What is the difference between Acular and Fiorinal?

Acular contains Ketorolac Tromethamine, while Fiorinal contains Aspirin and Butalbital and Caffeine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.