ACULAR vs DEMI-REGROTON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR and DEMI-REGROTON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	DEMI-REGROTON
Rating	72/100	70/100
Pharmacy pays	—	~$2.67 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	CHLORTHALIDONE AND RESERPINE
Manufacturer	Abbvie	Sanofi Aventis US
Dosage forms	Drops	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular demi-regroton

Rating

72/100

70/100

Pharmacy pays

—

~$2.67 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

CHLORTHALIDONE AND RESERPINE

Manufacturer

Abbvie

Sanofi Aventis US

Dosage forms

Drops

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular or Demi-Regroton?

By our independent rating, Acular scores higher — 3.6 vs 3.5 out of 5 for Demi-Regroton. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Acular and Demi-Regroton?

Acular contains Ketorolac Tromethamine, while Demi-Regroton contains Chlorthalidone and Reserpine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.