ACULAR LS vs TUZISTRA XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR LS and TUZISTRA XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR LS	TUZISTRA XR
Rating	72/100	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	CHLORPHENIRAMINE POLISTIREX AND CODEINE POLISTIREX
Manufacturer	Abbvie	Tris Pharma Inc
Dosage forms	Drops	Suspension, extended release
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	—
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular ls tuzistra xr

Rating

72/100

Pharmacy pays

—

Type

Active ingredient

KETOROLAC TROMETHAMINE

CHLORPHENIRAMINE POLISTIREX AND CODEINE POLISTIREX

Manufacturer

Abbvie

Tris Pharma Inc

Dosage forms

Drops

Suspension, extended release

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

—

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular Ls or Tuzistra XR?

Acular Ls and Tuzistra XR are tied at 3.6 out of 5 by our independent rating.

What is the difference between Acular Ls and Tuzistra XR?

Acular Ls contains Ketorolac Tromethamine, while Tuzistra XR contains Chlorpheniramine Polistirex and Codeine Polistirex — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.