ACULAR LS vs SERPASIL-ESIDRIX #1

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR LS and SERPASIL-ESIDRIX #1 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR LS	SERPASIL-ESIDRIX #1
Rating	72/100	70/100
Pharmacy pays	—	~$0.91 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	HYDROCHLOROTHIAZIDE AND RESERPINE
Manufacturer	Abbvie	Novartis
Dosage forms	Drops	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 6 to 15 hours (the label reports a range, not a single number)
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular ls serpasil-esidrix #1

Rating

72/100

70/100

Pharmacy pays

—

~$0.91 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

HYDROCHLOROTHIAZIDE AND RESERPINE

Manufacturer

Abbvie

Novartis

Dosage forms

Drops

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 6 to 15 hours (the label reports a range, not a single number)

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular Ls or Serpasil-Esidrix #1?

By our independent rating, Acular Ls scores higher — 3.6 vs 3.5 out of 5 for Serpasil-Esidrix #1. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Acular Ls and Serpasil-Esidrix #1?

Acular Ls contains Ketorolac Tromethamine, while Serpasil-Esidrix #1 contains Hydrochlorothiazide and Reserpine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.