ACULAR LS vs FIORINAL W/CODEINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR LS and FIORINAL W/CODEINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR LS	FIORINAL W/CODEINE
Rating	72/100	72/100
Pharmacy pays	—	~$0.78 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	ASPIRIN AND BUTALBITAL AND CAFFEINE AND CODEINE PHOSPHATE
Manufacturer	Abbvie	Allergan
Dosage forms	Drops	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 20 minutes (the label also states 0.33 hours) for aspirin itself
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular ls fiorinal w/codeine

Rating

72/100

Pharmacy pays

—

~$0.78 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

ASPIRIN AND BUTALBITAL AND CAFFEINE AND CODEINE PHOSPHATE

Manufacturer

Abbvie

Allergan

Dosage forms

Drops

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 20 minutes (the label also states 0.33 hours) for aspirin itself

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

Which is better-rated, Acular Ls or Fiorinal W/Codeine?

Acular Ls and Fiorinal W/Codeine are tied at 3.6 out of 5 by our independent rating.

What is the difference between Acular Ls and Fiorinal W/Codeine?

Acular Ls contains Ketorolac Tromethamine, while Fiorinal W/Codeine contains Aspirin and Butalbital and Caffeine and Codeine Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.