ACTOS vs PIOGLITAZONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ACTOS	PIOGLITAZONE
Rating	New	New
Pharmacy pays	~$2.77 /30	~$2.77 /30
Type	RX	RX
Active ingredient	PIOGLITAZONE HYDROCHLORIDE	PIOGLITAZONE HYDROCHLORIDE
Manufacturer	Takeda Pharms USA	Alphapharm
Dosage forms	Tablet	Tablet
Drug class	Peroxisome Proliferator Receptor Alpha Agonist	Peroxisome Proliferator Receptor Alpha Agonist
Boxed warning	Boxed warning	Boxed warning
Half-life	about 3 to 7 hours (parent drug)	about 3 to 7 hours (parent drug)
Treats	Type 2 Diabetes Mellitus	Type 2 Diabetes Mellitus

actos pioglitazone

Rating

New

Pharmacy pays

~$2.77 /30

Type

Active ingredient

PIOGLITAZONE HYDROCHLORIDE

Manufacturer

Takeda Pharms USA

Alphapharm

Dosage forms

Tablet

Drug class

Peroxisome Proliferator Receptor Alpha Agonist

Boxed warning

Half-life

about 3 to 7 hours (parent drug)

Treats

Type 2 Diabetes Mellitus

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Frequently asked questions

Which is cheaper, Actos or Pioglitazone?

Pharmacies pay about the same to acquire either one — roughly $2.77 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Actos and Pioglitazone?

Both Actos and Pioglitazone share the active ingredient Pioglitazone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.