ACTOPLUS MET vs ACULAR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ACTOPLUS MET and ACULAR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACTOPLUS MET	ACULAR
Rating	New	72/100
Pharmacy pays	~$0.74 /30	—
Type	RX	RX
Active ingredient	METFORMIN HYDROCHLORIDE AND PIOGLITAZONE HYDROCHLORIDE	KETOROLAC TROMETHAMINE
Manufacturer	Takeda Pharms USA	Abbvie
Dosage forms	Tablet	Drops
Drug class	—	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	None
Half-life	about 3 to 7 hours (parent drug)	about 5 to 6 hours
Treats	—	Allergic Conjunctivitis, Inflammation, Pain

actoplus met acular

Rating

New

72/100

Pharmacy pays

~$0.74 /30

—

Type

Active ingredient

METFORMIN HYDROCHLORIDE AND PIOGLITAZONE HYDROCHLORIDE

KETOROLAC TROMETHAMINE

Manufacturer

Takeda Pharms USA

Abbvie

Dosage forms

Tablet

Drops

Drug class

—

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 3 to 7 hours (parent drug)

about 5 to 6 hours

Treats

—

Allergic Conjunctivitis, Inflammation, Pain

Frequently asked questions

What is the difference between Actoplus Met and Acular?

Actoplus Met contains Metformin Hydrochloride and Pioglitazone Hydrochloride, while Acular contains Ketorolac Tromethamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.