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ACTONEL vs BINOSTO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ACTONEL and BINOSTO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

~$73.02 /30
~$7.76 /30

Type

RX
RX

Active ingredient

RISEDRONATE SODIUM
ALENDRONATE SODIUM

Manufacturer

Dosage forms

Tablet
Tablet, effervescent

Drug class

Bisphosphonate
Bisphosphonate

Boxed warning

None
None

Half-life

about 561 hours — roughly 23 days

Treats

Extramammary Paget Disease, Postmenopausal Osteoporosis
Extramammary Paget Disease, Postmenopausal Osteoporosis

Frequently asked questions

Which is cheaper, Actonel or Binosto?

Binosto costs pharmacies less to acquire — about $7.76 vs $73.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Actonel and Binosto?

Actonel contains Risedronate Sodium, while Binosto contains Alendronate Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.