ACTIVASE vs ZONTIVITY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. ACTIVASE and ZONTIVITY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACTIVASE	ZONTIVITY
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ALTEPLASE	VORAPAXAR SULFATE
Manufacturer	Genentech Inc	Key Therap
Dosage forms	Kit	Tablet
Drug class	—	—
Boxed warning	None	None
Treats	Arterial Occlusive Diseases, Intracranial Embolism and Thrombosis, Myocardial Infarction	Coronary Disease, Myocardial Infarction, Peripheral Arterial Disease

activase zontivity

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

ALTEPLASE

VORAPAXAR SULFATE

Manufacturer

Genentech Inc

Key Therap

Dosage forms

Kit

Tablet

Drug class

—

Boxed warning

None

Treats

Arterial Occlusive Diseases, Intracranial Embolism and Thrombosis, Myocardial Infarction

Coronary Disease, Myocardial Infarction, Peripheral Arterial Disease

Frequently asked questions

What is the difference between Activase and Zontivity?

Activase contains Alteplase, while Zontivity contains Vorapaxar Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.