ACTISITE vs CLINDESSE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACTISITE and CLINDESSE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACTISITE	CLINDESSE
Rating	New	70/100
Pharmacy pays	~$17.46 /30	$0.18 /g
Type	RX	RX
Active ingredient	TETRACYCLINE HYDROCHLORIDE	CLINDAMYCIN PHOSPHATE
Manufacturer	Schiff and Co	Padagis US
Dosage forms	Fiber, extended release	Topical
Drug class	Tetracycline-Class Antimicrobial	Lincosamide Antibacterial
Boxed warning	None	None
Half-life	—	about 2.4 hours
Treats	Acne Vulgaris, Bartonella Infections, Borrelia Infections	Acne Vulgaris, Actinomycetales Infections, Bacteroides Infections

actisite clindesse

Rating

New

70/100

Pharmacy pays

~$17.46 /30

$0.18 /g

Type

Active ingredient

TETRACYCLINE HYDROCHLORIDE

CLINDAMYCIN PHOSPHATE

Manufacturer

Schiff and Co

Padagis US

Dosage forms

Fiber, extended release

Topical

Drug class

Tetracycline-Class Antimicrobial

Lincosamide Antibacterial

Boxed warning

None

Half-life

—

about 2.4 hours

Treats

Acne Vulgaris, Bartonella Infections, Borrelia Infections

Acne Vulgaris, Actinomycetales Infections, Bacteroides Infections

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Frequently asked questions

What is the difference between Actisite and Clindesse?

Actisite contains Tetracycline Hydrochloride, while Clindesse contains Clindamycin Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.